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How GLP-1 Medications Work With these particular weight loss/T2D medications, active ingredients Semaglutide and tirzepatide mimic GLP-1 (Glucagon-like peptide-1), the naturally occurring hormone produced in the GI tract
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The trial demonstrated that once-weekly tirzepatide 10 mg and 15 mg offered substantial and clinically meaningful bodyweight reduction, with a safety profile similar to other therapies for weight management using incretin-based approaches
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